Publications

UK NEQAS for Leucocyte Immunophenotyping has contributed to the scientific literature for over three decades, advancing standards in flow cytometry, molecular haemato-oncology, and external quality assessment/proficiency testing worldwide.

Our publications span consensus guidelines, interlaboratory studies, and methodological research – covering areas from CD4+ T cell counting and CD34+ stem cell enumeration to PNH testing, measurable residual disease in haematological malignancies, and chimerism monitoring after HSCT. These collaborative works reflect our commitment to improving laboratory accuracy and patient outcomes through rigorous external quality assessment.

Association for Clinical Genomic Science (ACGS) guidelines for the classification of oncogenicity of somatic variants in cancer: recommendations by the UK somatic variant interpretation group (SVIG-UK)

Burghel GJ, Mason J, Baker K, Moloney K, McKeeve CH, Cartwright A, Brás-Goldberg AM, Travis D, Lewis S, Fairley JA, Williams J, Russell K, MacMahon S, Wragg C.

J Med Genet. Published Online First: 03 December 2025 doi: https://doi.org/10.1136/jmg-2025-111046

UK recommendations for chimerism testing and monitoring following allogeneic haematopoietic stem cell transplantation (HSCT): Best practice consensus guidelines from the British Society for Blood and Marrow Transplant and Cellular Therapies (BSBMTCT), NHS England Genomic Laboratory Hub (GLH) Haematological Malignancies Working Group, UK Cancer Genetics Group (UKCGG) and the UK National External Quality Assessment Service for Leucocyte Immunophenotyping (UK NEQAS LI)

Clark A, Clouston H, Rao K, Folarin N, De la Fuente J, Hamblin A, Olavarria E, Richardson D, Talley P, Potter V, Loke J, McVeigh T, Snowden J.

Br J Haematol. 2025 Sep 9. doi: https://doi.org/10.1111/bjh.70061. Epub ahead of print. PMID: 40926330

Estimation of the allowable total error of the absolute CD34+ cell count by flow cytometry using data from UK NEQAS exercises 2004-2024

Brando B, Whitby L, Gatti A, Whitby A, Di Credico F, Scott S

Clin Chem Lab Med. 2025 Mar 3;63(6):1190-1198 doi: https://doi.org/10.1515/cclm-2025-0065. PMID: 40021343.

European flow cytometry quality assurance guidelines for the diagnosis of primary immune deficiencies and assessment of immune reconstitution following B cell depletion therapies and transplantation

Kelleher P, Greathead L, Whitby L, Brando B; UK NEQAS Leucocyte Immunophenotyping Steering Committee; Barnett D, Bloxham D, deTute R, Dunlop A, Farren T, Francis S, Payne D, Scott S, Snowden JA, Sorour Y, Stansfield E, Virgo P, Whitby A

Cytometry B Clin Cytom. 2024 Nov;106(6):424-436. doi: https://doi.org/10.1002/cyto.b.22195

Epub 2024 Jun 28. PMID: 38940298.

Recommendations from the AML molecular MRD expert advisory board

Scott S, Devonshire A, Dillon R, Thiede C, Cross NCP, White HE, Lo Cascio L, Mokretar K, Potter N, Hourigan CS, Radich J, Corner A, Laloux V, Halliday G, Dilks D, Morrison T, Gilmour K, Cartwright A, Whitby L

Leukemia. 2024 Jul;38(7):1638-1641. doi: https://doi.org/10.1038/s41375-024-02275-x.

Epub 2024 May 23. PMID: 38783160; PMCID: PMC11216975.

Assessment of acute myeloid leukemia molecular measurable residual disease testing in an interlaboratory study

Scott S, Dillon R, Thiede C, Sadiq S, Cartwright A, Clouston HJ, Travis D, Mokretar K, Potter N, Chantry A, Whitby L

Blood Adv. 2023 Jul 25;7(14):3686-3694. doi: https://doi.org/10.1182/bloodadvances.2022009379. PMID: 36939402; PMCID: PMC10368676

Implementation of the updated NICE haematological cancers (NG47) improving outcomes guidelines across Specialist Integrated Haematological Malignancy Diagnostic Services (SIHMDS) in England: a UK NEQAS LI survey

Cartwright A, Snowden JA, Whitehouse H, Scott S, Whitby L

J Clin Pathol. 2023 Sep;76(9):618-623. doi: https://doi.org/10.1136/jclinpath-2021-208075. Epub 2022 May 4. PMID: 35508367; PMCID: PMC10447389.

Evaluation of multiple myeloma measurable residual disease by high sensitivity flow cytometry: An international harmonized approach for data analysis

Soh KT, Came N, Otteson GE, Jevremovic D, Shi M, Olteanu H, Natoni A, Lagoo A, Theakston E, Óskarsson JÞ, Gorniak M, Grigoriadis G, Arroz M, Fletcher M, Lin P, Ludwig P, Tembhare P, Matuzeviciene R, Radzevicius M, Kay S, Chen W, Cabrita C, Wallace PK

Cytometry B Clin Cytom. 2022 Mar;102(2):88-106. doi: https://doi.org/10.1002/cyto.b.22053. Epub 2022 Jan 10. PMID: 35005838; PMCID: PMC10105368.

Assessing the impact of the 2017 European LeukemiaNet recommendations on FLT3 allelic ratio calculation and reporting in acute myeloid leukaemia

Cartwright A, Scott S, Francis S, Whitby L

Br J Haematol. 2022 May;197(3):e35-e37. doi: https://doi.org/10.1111/bjh.18023. Epub 2022 Jan 3. PMID: 34981510

Assessment of droplet digital polymerase chain reaction for measuring BCR-ABL1 in chronic myeloid leukaemia in an international interlaboratory study

Scott S, Cartwright A, Francis S, Whitby L, Sanzone AP, Mulder A, Galimberti S, Dulucq S, Mauté C, Lauricella C, Salmon M, Rose S, Willoughby J, Boeckx N, Pallisgaard N, Maier J, Leibundgut EO, Zizkova H, Ling Goh L, Duong C, Tang WF, Ma E, Shivakumar Y, Beppu L, Bhagavatula P, Chantry A

Br J Haematol. 2021 Jul;194(1):53-60. doi: https://doi.org/10.1111/bjh.17521. Epub 2021 Jun 10. PMID: 34114218.